5. The Spectacular Spider-Man #173: Doc Ock goes to visit Aunt May so that he won't be alone for the holidays, but is jumped by Spider-Man who's had a very bad day.
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4. The Amazing Spider-Man #398 & The Spectacular Spider-Man #221: Issues three and four of the Web of Death story arch. Doctor Octopus attempts to save Spider-Man from a virus the Vulture infected him with. He succeeds, but is immediately killed by Kaine, a spider-clone gone wrong.
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3. Spider-Man/Doctor Octopus: Out of Reach: Doctor Octopus "enlists" the help of child genius Brigham Fontaine to help him open a vault that Fontaine invented. He develops paternal emotions toward the boy and sees a little of himself in his pupil. He has to decide whether or not to lead the boy down his own path, or do what's right for Fontaine's future.
2. Spider-Man Unlimited #3: The first time Octavius's life was detailed out pre-Octavius, told from the perspective of an obituary writer hoping for a scoop. Not only is the story of Octavius itself wonderful, the way in which it's told, plus the message of how AIDs can affect anyone, makes this a story to remember.
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1. Spider-Man Unlimited #18: "Her Name Was Stunner", a three page excerpt at the end of what is a well-drawn retelling of Ock's origin story and his past up to his rebirth, is written by Stan Lee and is not only a wonderful testiment to Octavius's love for Angelina Brancale, but his vast support for the underestimated and scoffed portions of society.
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